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Literature summary extracted from
- Matrix metalloproteinases, MMP-7 and MMP-26, in plasma and serum of control and preeclamptic umbilical cord blood (2010), Eur. J. Obstet. Gynecol. Reprod. Biol., 150, 152-156.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.B7 | Ca2+ | required | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.B7 | pro-MMP-9 + H2O | Homo sapiens | MMP-26 can activate MMP-9 by cleavage of some sites in pro-MMP-9 | MMP-9 + MMP-9 propeptide | - |
? | |
| 3.4.24.23 | additional information | Homo sapiens | MMP-7 participates in activation other members of the MMP family | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.B7 | Homo sapiens | - |
- |
- |
| 3.4.24.23 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.24.B7 | additional information | MMP-26 is only active after treatement with reducing agents | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.B7 | additional information | MMP-26 exists in the form of complexes with other extracellular matrix components and/or their tissue inhibitors in control and preeclamptic subjects, overview | Homo sapiens | - |
| 3.4.24.B7 | plasma | from control and preeclamptic umbilical cord blood | Homo sapiens | - |
| 3.4.24.B7 | serum | from control and preeclamptic umbilical cord blood | Homo sapiens | - |
| 3.4.24.B7 | umbilical cord | - |
Homo sapiens | - |
| 3.4.24.23 | blood | from umbilical cord, MMP-7 quantification, overview | Homo sapiens | - |
| 3.4.24.23 | serum | from umbilical cord, MMP-7 quantification, overview | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.B7 | casein + H2O | zymography | Homo sapiens | ? | - |
? | |
| 3.4.24.B7 | pro-MMP-9 + H2O | - |
Homo sapiens | MMP-9 + MMP-9 propeptide | - |
? | |
| 3.4.24.B7 | pro-MMP-9 + H2O | MMP-26 can activate MMP-9 by cleavage of some sites in pro-MMP-9 | Homo sapiens | MMP-9 + MMP-9 propeptide | - |
? | |
| 3.4.24.23 | casein + H2O | non-specific substrate used in zymography | Homo sapiens | ? | - |
? | |
| 3.4.24.23 | additional information | MMP-7 participates in activation other members of the MMP family | Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.24.B7 | MMP-26 | - |
Homo sapiens |
| 3.4.24.23 | MMP-7 | - |
Homo sapiens |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B7 | 37 | - |
assay at | Homo sapiens |
| 3.4.24.23 | 37 | - |
assay at | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.B7 | 7.4 | - |
assay at | Homo sapiens |
| 3.4.24.23 | 7.4 | - |
assay at | Homo sapiens |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.24.B7 | physiological function | MMP-26 participates in activation other members of the MMP family | Homo sapiens |
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